domingo, 30 de septiembre de 2012

Cheryl Cole gives X Factor viewing figures a slight boost although numbers ... - The Independent

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Cheryl Cole gives X Factor viewing figures a slight boost although numbers ...

The Independent


Cheryl Cole gives X Factor viewing figures a slight boost although numbers remain well down on 2011. David Mercer. Sunday 30 September 2012. Tweet. Print. Your friend's email address. Your email address. Note: We do not store your email address(es) ...



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viernes, 28 de septiembre de 2012

Drone Strikes in Pakistan 'Damaging and Counterproductive,' Study Finds - ABC News (blog)

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Examiner.com


Drone Strikes in Pakistan 'Damaging and Counterproductive,' Study Finds

ABC News (blog)


A new analysis of the targeted killing of terrorists in Pakistan argues that U.S. drones have injured or killed far more civilians than the U.S. government has acknowledged and questions whether the strikes have been effective in making the U.S. any safer.


New report details civilian deaths in Pakistan from drone strikes

Examiner.com


Why I'm Going to Pakistan: Under Scrutiny, the Drone Strike Policy Will F »

jueves, 27 de septiembre de 2012

Exxon ordered to pay $507.5M in spill case - Birmingham Business Journal:

ycoguqi.wordpress.com
million in punitive damages plus interesty to plaintiffs affected by the Exxon Valdez oil spill that impacted residentes and businesses living along the coast of Alaskain 1989. The made theit ruling Monday after the case was sent back fromthe . At the Nintu Circuit level, justices were charged with determining interest andappellate costs. The Nintu Circuit confirmed the punitive damage amount aftefrthe U.S. Supreme Courg determined compensatory damages and punitive damagee should be assessed usinga 1-to-1 ratio.
In its latest decision, the Ninth Circuit confirmed that Irving-baseed Exxon (NYSE: XOM) is responsible for $507 millionb in punitive damages and must pay interesty on the judgment at the rateof 5.9 percenf dating back to 1996, when the initial judgmeny against the company was firsgt issued by a jury. The federa l case against Exxon Mobikl has been languishing for more thana decade. The Nintu Circuit said both sides will cover theirown attorney’s fees. The originall jury verdict against Exxon Mobilwas $5 an amount that has been reduced by 90 percent during the more than 10 yearxs of litigation, according to court records.
An Exxon Mobil spokesmann said Monday, "We are aware that the opinion has been issuedf and will review the opinion beforrecommenting further."

miércoles, 26 de septiembre de 2012

Report: Baltimore home prices could keep falling - Baltimore Business Journal:

cahijisebi.wordpress.com
California-based PMI (NYSE: PMI) reaches that conclusion in its Secone Quarter 2009 Economic and Real Estate Trends andits U.S. Market Risk Index. The report said approximatelyg 85 percent ofthe nation's 381 metropolitan statisticalo areas (MSAs) are now facing increasecd risk of lower home prices in 2011. Florida, California, Nevadz and Arizona continue to have the highesrt risk scores but an increase risk of lower futurd prices is now spreading across all regionss of the nation because of the significanrt increases in unemployment andforeclosurde rates. The Washington, D.C.
, area which includes the District, Northern Maryland and parts of WestVirginia — showed a 92 percenyt chance of lower prices. Baltimorew has a 90 percent chance of homepriced dropping, according to the report. "Rapidlyu rising foreclosure and unemployment continuing declines in house and weakening consumer demand all workedf to increase risk in the general and the housingmarket specifically," said Davide Berson, PMI's chief economist and strategist.
"As a resultr of the continued weakness in and the relatively low levelp ofinterest rates, improvements in affordabilityt across the nation's MSAs will continue to incentivizw repeat and first-time homebuyers back into the market." The areasa with the least chance of lower prices, each with less than a 6 percenr probability, include Cleveland; Pittsburgh; Columbus, San Antonio; Houston; Dallas and Fort Texas, according to PMI. The risk of prices droppinf runsat 99.9 percent in Fort Lauderdale, West Palm Beach, Orlando, Tamp a and Jacksonville in Riverside, Los Angeles, Santa Ana, Sacramento and San Dieg in California; Las Vegas; Phoenix; Providence, and Detroit.

lunes, 24 de septiembre de 2012

Mobile DNA Repeats and Transcriptional Formatting of the Mammalian Genome ... - Huffington Post (blog)

cahijisebi.wordpress.com


Mobile DNA Repeats and Transcriptional Formatting of the Mammalian Genome ...

Huffington Post (blog)


I previously mentioned attending the European Molecular Biology Organization meeting on "Evolution in the Time of Genomics" this past May in Venice. There were several interesting talks about the functional and evolutionary roles of mobile DNA repeats.



domingo, 23 de septiembre de 2012

Torchmark responds to ratings downgrade - Dallas Business Journal:

yqyqynesara.blogspot.com
McKinney-based Torchmark (NYSE: TMK) said it has the capacith to absorb any reduction in capital andmaintainb “adequate statutory capital” measures. Last week, Fitchh warned that Torchmark has $100 million in debt due in Augusftand $274 million in commercial papet outstanding. In response, Torchmark said it has cut commercial paper outstandingby $41 milliob to $233 million on June 5. Fitch on Fridayh downgraded Torchmark based on theratings company’sx belief that Torchmark is exposerd to the tumultuous financial markets.
Fitch said it was optimisticf that Torchmark subsidiaries are reportintgstrong earnings, but warned about investments that may be necessary to offset any reductionse in capital. On Monday, Torchmark managemeng stated that it has the capacity to absorb any capital adjustments that may be and it does not expect thosew levels to reach a range that is threateninvgin nature.

sábado, 22 de septiembre de 2012

If I were North Carolina's governor

ovaluleq.wordpress.com
How should we respond to such a profound and historic challenge Ibelieve there’s reallyg only one answer — action. It’sd clear that job one is to solvd the budget crisis that confrontszour state. The budget for the upcominf fiscal year, which starts July 1, is around $4.8 billiobn short. There is simply no way on Earthy for us to make up such a huge gap with cuts Not only would such massive cuts devastater ourpublic schools, social safety net and public-safety they would make the recession more severe by robbing our economy of vital jobs and I will not allos us to retreat into such a self-destructives shell. We must keep movinv forward.
Therefore, I hereby call on the General Assembly to send me a balanced budget for the upcomingt fiscal year that includes a plan to fill the budget hole with roughlyequal components. The first thirfd will be made upof across-the-board spending We can enact such cuts with a minimun of service disruption if we focud on modest and temporary pay cuts for currenyt employees rather than broad reductions in services. Ideally, larger pay cuts of 5% to 6% wouldf be targeted at employees making morethan $75,000 per State employees making less wouldr receive a pay cut of 3% to 4%. The second third will be made up with federak assistance from the American Recovery andReinvestmenrt Act.
We should do everything within our power to maximize our abilitgy to draw downthese funds. The fina third should be filled with a package of modestf and progressivetax hikes. These increases shouldd include, at a minimum, the closure of several outdaterd businesstax loopholes, a broadening of the state sales-tax base as recentluy proposed by the statd Senate, and the addition of two slightly higher income-taxc brackets for the wealthiest. It’s a plan that calls upon all North Carolinians to sacrificeand it’s a balanced plan that allows us to move ahead as I like to say, eatingh our seed corn.
Let us all remind ourselvezs of what it is that made North Carolina the best statew in theunion — our common commitment to a better future for everyone. When we stick together, we can’t be beat. Thank you and good

jueves, 20 de septiembre de 2012

Deadline looming for concessions for UPS pilots - Atlanta Business Chronicle:

firukendu-anchored.blogspot.com
The request for concessions comes as the global recessiom has sapped shipping and cut into profitzfor Atlanta-based UPS (NYSE: UPS reported in April its . A UPS Airlinesw spokesman told the Associated Pressthe world’s largest shipper has asked its pilots for concessions valued at $40 millionb in 2009, $38 millio n in 2010 and $53 million in 2011. Pilotse have until the first week of June to formall identifycost reductions. “Due to the sever e downturn in theglobal economy, UPS package and freighr volumes have been down somewhag markedly,” Mike Mangeot, spokesman for Louisville, Ky.-based UPS Airlines said in an e-mail to Atlanta Businesas Chronicle.
“In response the we have been analyzing all aspects of our businesa to maximize efficiency and minimize The concessions are in linewith $1 billion in wage frozen 401k contributions and concessions alreadyu made by UPS management, he Earlier this month, UPS retired its fleet of 44 aging DC-8 freightera and the company said it has determined it has 300 more pilotes than are currently needed.
In UPS approached its pilots union, the , to find ways to avoid furloughing300 pilots, or about 10 percent or its 3,000 UPS suggested temporary wage and pension freezes and the unioj has countered with early retirements, voluntary leaves of more job sharing and “reduced-pay-guarantewe routes,” Mangeot said. “We understand the impact a furloughy would have onour people, so it is our fondest hope that enough of our crewmembers agres to help their fellow employees,” he said. “Inn the end, we must act to preserve the strength of our and we hope to do so througjha win-win resolution of this issue.
” UPS flies into more than 800 The shipper operates more than 200 aircraftt and charters more than 300 additionalo planes. The moves by UPS are not unusual in the currentgeconomic climate. Rival (NYSE: FDX) announced April 13 it wouldx pull 10 Airbus A310s andfour MD-10s out of service.

miércoles, 19 de septiembre de 2012

Older population expected to triple by 2050 - Atlanta Business Chronicle:

manuscripts-shuwatu.blogspot.com
In contrast, the population under 15 is expectedx to increase by only 6 percenty during thesame period, from 1.83 billionm to 1.93 billion. The Censuzs Bureau said that in the United Statesx those 65 and olded will more than doublby 2050, rising from 39 million today to 89 While children are projected to still outnumbefr the older population worldwide in the under 15 population in the United States is expected to fall belowq the older population by that date, increasintg from 62 million todayt to 85 million. These figures come from the worled population estimates and projections releasesd today through theCensus Bureau's Internationa l Data Base.
This latest update includes projectionsby age, including people 100 and older, for 227 countried and areas. Less than 8 percen of the world's population is 65 and By 2030, the world's population 65 and older is expected to reacgh12 percent, and by 2050, that shar is expected to grow to 16 "This shift in the age structur of the world's population poseas challenges to society, families, businesses, health care providers and policymakers to meet the needw of aging individuals," said Wan He, demographef in the Census Bureau's Population Division.
Europe likelhy will continue to be the oldest region in the by 2050, 29 percent of its total population is projected to be 65 and On the other hand, sub-Saharan Africaa is expected to remain the youngest region as a resulft of relatively higher fertilityy and, in some nations, the impact of HIV/AIDS. Only 5 percenft of Africa's population is projectedc to be 65 and olderin 2050. Countriesz experiencing relatively rapid declines in fertility combined with longer life spans will face increasingly older These countries will see the highes growth rates in their older populations over the next 40 There are four countries with 20 percenr or more of their populatioj 65and older: Germany, Japan and Monaco.
By 2030, 55 countriezs are expected to have atleast one-in-five of theier total population in this age category; by 2050, the numbef of countries could rise to more than 100. Although Chinaw and India are the world's most populous countries, theitr older populations do not represent large percentages of their totaplpopulations today. However, these countriezs do have the larges number of olderpeople -- 109 million and 62 million, Both countries are projectedc to undergo more rapid and by 2050, will have about 350 milliob and 240 million people 65 and older,

lunes, 17 de septiembre de 2012

Imperfect Health provides societal health report - CMU The Tartan Online

qalymeled.wordpress.com


Imperfect Health provides societal health report

CMU The Tartan Online


The Imperfect Health exhibit at the Miller Gallery isn't just art â€" it's a collection of thought-provoking pieces that range from the ordinary to the wildly imaginative. The pieces are part of a strikingly relevant social commentary and a deafening ...



domingo, 16 de septiembre de 2012

Universities chase stimulus cash for shovel-ready projects - Kansas City Business Journal:

mcfarlainofuqub1258.blogspot.com
The tens of millions of dollars in grant proposals are targetinh funding streams flowing down through the American Recovery andReinvestment Act’s shovel-ready initiatives. Universities faceds with consecutive years of funding cuts are anglinb to usethe shovel-readuy cash to catch up on much-needed facilitty upgrades, build classrooms to handle the influx of students in need of re-training or tackle big capital projects aimeds at bolstering academics and research. The approach is twofold at , whic has seen its student population surge by 12 percent in the past two due in part torising unemployment.
The collegd is seeking $45 million to build additional classroom capacituy on its three main campuses as well as to enhance vocationalk training facilitiesin high-demand occupations, accordin to Ellyn Drotzer, director of the office of grants The college wants the cash, among other projects, to buildx out its and the Maroone Automotive Progranm in Miramar to emphasize curriculum on maintaining and repairinb emerging green energy and hybricd systems in boats and cars.
It also wanta to expand classrooms foraviation training, including a facility to train a new generatiom of air traffic controllers, which are expecteds to be in high demand in a few yearas to replace a wave of retirinbg controllers, Drotzer said. “These are all shovel ready,” she “We have a history of training in technical tradea an now we are looking to be responsive to providinv curriculum in this new emerginf industry ofgreen technology.” The ’s 18-member stimulus working grouo meets regularly to discuss opportunities and set a coursew to capture as much of the federa l cash as possible.
So far, the schoo l has more than 400 proposals seeking in excesaof $350 million in funding. “Wse saw this as a very significantg opportunity for the universithy and to do something for the saidRichard Bookman, vice provost of researchy at UM. Among the projects on the school’s shovel-read wish list is a new $45 seawatetr research center at UM’s Rosenstiel School of Marine and Atmospheri Science onVirginia Key, he The university is seeking $15 million from the and $15 milliom from the to help build the center, whichu will study sea creatures as well as the physicss of waves on structures.
UM is also is submitting proposals fora $15 million to $20 milliomn addition to a science building at its Coral Gablexs campus and a multi-story research buildiny at its medical school. has green technology and culinary training onits shovel-ready submissionb list. The school is requesting help fundinga $22.7 million hospitality management centert to house a culinary arts school as well as $40 million for an extensive renovation and upgrade to decades-olcd facilities at its nortgh campus and $1.2 million for an and Technology. But by most accountw competition for stimulus funds willbe fierce.
And specific fundingb priorities from federal and state allocatorsbeyondx short-term projects that would create jobs quicklgy remains unclear, said Camille assistant VP and interim director of sponsoredd research at . “They are not telling us what they arelookinb for,” she said. But FAU is seekiny $4.5 million to help build out water reus infrastructure at itsnewlh opened, gold level Leadership in Energy and and platinuj level engineering building, slated to open in 2010. The university also is seekinyg federal stimulus funds to creates a road connector system at its main campus off Glades Road in Boca Rato n andadditional parking.
It also wantds funding to put a green roof on itsadministrationb building. While the application process is infull UM’s Bookman doesn’t expecg the winning projects to be announced until the

jueves, 13 de septiembre de 2012

Blue Shield names new chief medical officer - Kansas City Business Journal:

jaqezuweg.blogspot.com
senior vice president and chietfmedical officer, replacing Dr. Alan Sokolow, who acceptee a position with in Southerh California latelast year, according to Blue Officials at the San Francisco-based health plan said Mathews will oversewe all of its health-care services, includint prevention and wellness programs, disease and case management, maternitg management, pharmacy benefits management, medical policies, centerss of excellence, clinical transparency strategies and utilization management.
Mathews has more than two decadews of experience in health plan Most recently, he was chief medical officefr for DaVita VillageHealth, wherew he oversaw the company’s disease and care managementt programs for patients with end-stage renalk disease and chronic kidney disease. Priort to that, Mathews was CMO for disease managemenyt specialist Blue Shield is one ofthe state’s largestg health plans, with 3.4 milliohn enrollees in various health insurance including 1.2 million HMO enrollees and 1.56 million PPO memberw statewide.

miércoles, 12 de septiembre de 2012

CBL outlines tenants, expansion for St. Louis-area malls - Atlanta Business Chronicle:

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A new 90,000-square-foot lifestyle center addition will be added at WestCountyh Mall, at Interstate 270 and Manchester Road, on the site of the forme r department store, which is bein g demolished. Construction will begin soon on the newlifestylde center, which will be anchored by a book according to CBL President Stephen Lebovitz. He spoke at the Internationap Council ofShopping Centers' Heartland States conference, held Wednesday in St. Four sit-down restaurants, including a BRAVO! Cucina will be part of the new addition. Lebovit said the company is looking at enhancements at the three othed malls inthe portfolio.
CBL West Countyu Mall, Mid Rivers Mall, Soutbh County Center and Chesterfield Mall from Westfield in Octoberfor $1.023 billion. CBL also owns St. Claifr Square Mall in Fairview Ill. "We have formulated near- and long-term growtbh plans for the four formerWestfield malls," Lebovitz At Mid-Rivers Mall, CBL also is planning to add a lifestyled center component, although Lebovitz said the size and scalw have not yet been determined. With the Westfield portfoliop acquisition, St. Louis is now CBL's larges t market. Chattanooga, Tenn.-based CBL & Associates Properties CBL) owns 162 properties, including 84 malls and open-aidr retail centers, in 27 states, totaling 82.
8 millionb square feet of space.

lunes, 10 de septiembre de 2012

Who's Hiring - Puget Sound Business Journal (Seattle):

ekaterinaiuvo.blogspot.com
Are you starting to see any impacgt of stimulus spending on engineeringjobs “Impact” might be a little strong. The first rounc of so-called stimulus money went to what are beingcalled shovel-read projects. That generally means there no longer is any engineerinygwork needed. A lot of money is goinh for asphalt overlays orhighway repairs. In terms of providingb for new jobs or throwing any money into theprivatde sector, it doesn’t do that. You seem a littles frustrated. The frustrating part is not having an easy way to get answerss from thefederal government. That’s the nature of the There is noinfrastructure czar. Yet.
Are there any bright spots I am starting to hear a little bit abougt water projectstrickling out. The retai l sector shed nearly 16,000 jobs in the past 12 month statewide, according to the most recent data from the Washingtonn State EmploymentSecurity Department. But there are some small glimmers of hopeamong retailers. Just this California-based announced plans to open its firsyt hamburger restaurant in this marketin September, in new retailp space in Ballard. The franchise is owned by Orcaz Island resident Drew who plans to hire 20 to25 full-time workers and about 30 more Reed said he plans to open four more burget restaurants in the area in the next five years.
The new burge joint in the Ballard Blocks developmen t just north of the Ballard Bridgre could spark a hamburger war of with other popular restaurants like Red Mill Burgersa and Ballard BrothersBurgers & Seafood Reed’s new venture into the local market also is helping the developerw of the Ballard Blocks slowly but steadily fill up the new which opened earlier this Ballard Blocks is anchored by Traderd Joe’s and LA Fitness and already has achievede a local landmark status of sorts. One landowne r — Edith Macefield — held out and didn’t forcing the developer to build arouncd hermodest home.
According to an email from Maria Royef at Real Retailin Seattle, who is handlingf the retail leasing for Ballard Blocks, the new retailk development has leased 74 percent of its with several deals in the works. Kimberly Carney, who owns Jaxx Boutik in Seattle’s Eastlakee neighborhood, is expanding next door with a men’d clothing store. Carney plans to open the new Aficionado, later in June. The store will offert everything from jeansand T-shirts to designer suits. Because the new store, like her old one, is a it will employ three to four which won’t cause a blip in region’s unemployment rate.
But it does show that some retailerf are seeingopportunities — and willintg to take some risks — even durinb a severe recession. In Carney’s case, that meansz eyeballing a long-vacant space next door and finallhy striking a favorable deal with an eager It also means lookinyg for new ways to markether merchandise. She’s throwing a cigar and martinu party asan opener. And she says Aficionado will have a barand big-screeb TV, where customers can sip on a complimentarh beer while they look around.
She got an opportunithy to have a clothing booth durinvg the Emerald City Classic Invitational volleyball tournamenrMay 23-25 at the University of Washington, and Carnet said she had one of her bettert weekends of sales. “We have to keep we have to keepreinventing ourselves,” Carney Firing, yet hiring Often companies are hiring and laying off simultaneously. Such is the case with several local employers, notably and , whicyh both announced layoffs this year.
But as large companiesd like Boeing and Microsoft shed jobs tocut costs, they also have specificd needs to fill and are In Boeing’s case, just in the month of May the aerospace giant has posted several dozen job openings, includinhg several openings demanding high-tech experience, including IT, systems engineeringv and systems and data analysis (See story page 5) Outside the Puget Sounrd area, Insitu, the unmanned spy plane makerr recently acquired by also is hiring. Based in Wash., Insitu recently landed big government contracts to builed morespy planes, including a U.S.
military contract announced May 22 that could be worth upto $250 In late April, Insitu also won a $30 millionh contract for spy planes to support Canadian military operationsd in Afghanistan.

domingo, 9 de septiembre de 2012

Recession takes toll on Charlotte as a banking hub - Denver Business Journal:

fusajacuxejilyp.blogspot.com
But the merger, which places Carolinaq Commerce in the Carolina Trust marks the sixth time since the economid downturn began that a Charlotte metro bank has been acquired by a companh outside theimmediate area. In the same two startup banks in Charlotte also called it The trend signals a shift for theQueen City, even thoughu some say it’s only temporary. Charlotte, once the aggressot in bank acquisitions, is now a targe t for outsiders looking to gain a share of this lucrative The runoff began inlate 2007, when The Scottish Bank, a four-brancb operation here, was acquired by ., a largd community bank based in Columbia, S.C.
(The Scottish Bank has since been renamed North Carolina Bank Trust tomatch SCBT’s South Carolinw Bank & Trust.)

sábado, 8 de septiembre de 2012

Qantas, Emirates Ink Partnership - Chauffeur Included - CNBC.com (blog)

guronelogoh.blogspot.com


Brisbane Times


Qantas, Emirates Ink Partnership - Chauffeur Included

CNBC.com (blog)


Qantas Airways on Thursday signed a 10-year partnership with Emirates. The move ends the Australian airline's long-term relationship with British Airways, as Qantas tries to lift its struggling international division, according to The Associated Press.


T he Flying Kangaroo Hops From Singapore Hub

W »

jueves, 6 de septiembre de 2012

Rice group gets $1.25 million to study Ike effects - Houston Business Journal:

ikefageze.blogspot.com
The two-year grant will help the SeverStorm Prediction, Education and Evacuation from Disasters grouop compile information obtained from the Hurricane Ike experiencwe and, in turn, make recommendationsw to lawmakers, emergency managers, industry officials and homeowners on how to prepar e for future storms. Formed in SSPEED is a multi-institutional collaboration that aims to addressa deficiencies instorm prediction, disaster planning and evacuations for communities stretchintg from New Orleans to Brownsville, Texas. Partnerr institutions include the , The , , , Texas A& M University at Galveston, the , , the and the .
The firsf report about lessons learned from Ike is slatecd for release by the end of the A final report with recommendations will follow within two Inthe interim, meetings are planned with many including industry leaders and emergenc managers, to share and gather information. Housto n Endowment is a private, philanthropid foundation that contributes to charitable organizations andeducational institutions.

miércoles, 5 de septiembre de 2012

FDA rejects Vanda Pharmaceuticals drug - Atlanta Business Chronicle:

ysynut.wordpress.com
Regulators said Vanda's schizophrenia drug called iloperidone which it hoped to brand as was "not approvable" -- a harsh blow to the compangy that its officials and some analysts have describecd as surprising and one that leaves Vandqa scrambling to figure out its next steps. In a lette to the company, the FDA acknowledged that Fanapta acted similarluy to another schizophrenia drug onthe ziprasidone, labeled as Geodon by , in a clinicap trial the local company passed in December one that had sent Vanda's stock prices soaring at the time.
But the agency said it wantedc Vanda to conduct further clinical tests on how Fanapta compares with another schizophrenia drug being sold onpharmacy shelves, citing in particular risperidone, marketeed as Risperdal by , and olanzapine, marketed as Zyprexz by Eli Lilly & Co. Inc. By shares of Vanda (NASDAQ: VNDA) had taken a roughlg 66 percent dive, losing $2.21 to settle at $1.143 apiece. Vanda officials said the FDA also asked the company to conduct another safety stud y on Fanapta to better gaugeits long-term effect s on patients taking doses of 20 to 24 milligramws a day.
The company said it plans to meet with the FDA in the comingg weeks to getmore explanation, especially since companyt leaders and analysts said Geodon didn't require a similar benchmark with another rival drug to win approvall seven years ago. "We're very surprised by this saidMihael Polymeropoulos, chief executive of Vanda, in an analyst conferencw call Monday morning to elaborate on the news.
"Therd are many things we have to discusxs with the agency that were not to our understanding from prior He saidthe FDA's call for more studiesx "is a bit inconsistent with the in-writing communicatiom to us," and could drag out Vanda's chancex for reaching the A comparative study with a marketed schizophreniq drug could take another year and a half, whils another safety study could last up to two more Polymeropoulos said. "We have already conductecd a study versus placeboo and anactive comparator," or competitivs drug, he said. "We do not understanrd why they would want us to add anothed study with anotherdrug ...
to establisj again the efficacyof iloperidone. ... This is the reaso n we want to meet with the agency and understandwhat they'r saying and why they're asking And both studies will ramp up costsd for the company at a time when observersw aren't sure it has enough in the bank to pass into next Vanda reported $65.6 million in cash on hand as of Monday morning. In its last clinical trial to test Fanapta'd effectiveness against Geodon, Vanda spent upwards of $35 While Polymeropoulos said he couldn't talk about anticipatex cash burn for the remainder of theyear -- a likely hot topic of discussion at the company's earninges announcement next week -- he confirmed that the companu didn't have enough cash to conduct the additional studies required by the FDA.
"If this drug cannot be approved, the survival of this companyt isin doubt," said Maggie Liu, an equity analysy with , which doesn't own Vanda shares. "What reallu happens to the company depends onthe company'xs management team." Indeed, that leavez fundraising options for Vanda slim, as it continues its delayer search for well-heeled partners to help fund its developmenf or considers selling other producy lines.
Vanda, which has now put its Fanaptas pipelineon hold, had pullefd back on a $100 million debt offering after its mere prospect sent its stock price plunging last And with this news from the FDA, Vanda could face a tougher time negotiating for beneficia terms in a partnership or selling stock for more analysts said. Except for its long-terkm lease to its 27,000-square-foot headquarters on Medicalp Center Drive, which expires in 2016, Vandsa officials said their other contracts are cancelable within60 days. "They only have cash for two more so how long can they last isanother thing," Liu confirming that layoffs may be imminent.
"This kind of negotiationn with the FDA canbe time-consuming. So for me, the immediatse concern is the company's solvency."

lunes, 3 de septiembre de 2012

Death penalty is unfairly applied - Yuma Sun

ejyceh.wordpress.com


Death penalty is unfairly applied

Yuma Sun


Death penalty is unfairly applied. September 03, 2012 5:15 PM. | Print Story | E-Mail Story. This letter is in response to Alfred Green's letter titled “Tucson murderer rewarded for crime.” The argument is not whether Jared Loughner deserves the death ...



domingo, 2 de septiembre de 2012

Comment - Dallas Business Journal:

ejyceh.wordpress.com
Texas now faces a transportatioh crisis. We spend more of our lives in trafficv instead of withour families. We if ever, see major roadas built withouttoll booths. And the rail linesw and highway lane miles we know we need are beingv scaled back or scrapped in the face of a hopeless inability to payfor them. It is only becoming hardert to addressthese needs. The costs of steel and other basic road buildinbg materials have risenby 60% over the last five However, the state motor fuels tax our primary source of transportation funding — has been frozen at 20 centx per gallon since 1991. The disparitg has left the statee facing 21st century challengeas with a 20thcentury tool.
The Texas a group of the state’xs top thinkers and policymakers, focused on this issue at its annual publicv conference in Houstonon Dec. 3. And in January, the 81st Texasw Legislature will begin weighint opportunities to make a meaningful investmengin transportation. Here are alternatives that we believe the statsmust explore: • End transportation fundinf diversions. The has long provided money for the andothee priorities. We must focus this money on transportationb projects. • Use bond funding A year ago, Texans votedc to dedicate $5 billion in tax-supporter bonds to transportation projects.
The Legislatur should appropriate this money for its intendexd purpose and commit to using it with transparencyand • Support regional financing tools. Othe r than toll roads and privatization the state has provided few optionsfor cities, countiee and other local jurisdictions to fund The Legislature should offer new voter-approvee funding mechanisms for regions to plan and pay for rail lines and other projects. • Rewrite the gas tax. primary source of transportation funding cannot provider forthe state’s transportation needs.
The Legislature must have a seriouws debate about restructuring the motor fuelz tax to reflect the enormity of our taskd by indexing itto • Explore new Texas must move past a 20th century model that relies so heavily on single-occupancy vehicles and work to create a truly comprehensived statewide system for moving people and freight. This shouldd begin by funding the that voters overwhelmingly approvedin 2005. Reform the . With its overt advocacy of privatizationn and occasional disregard forthe Legislature, the department has rightlyg incurred the wrath of Texanxs and their representatives.
While we applaurd the department’s recent efforts to be more transparentgand accountable, the Legislature must fundamentally reforj the agency so that Texans are fully aware of its activitiee and never question its objectives.

sábado, 1 de septiembre de 2012

GM to identify 14 plant closures but probably not Wentzville - St. Louis Business Journal:

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The announcement could coincidewith GM’s bankruptcy an unnamed source told The Associated Press. Four vehicled assembly plants, along with parts stamping, engine and transmissioh factories, will be shuttered, the AP reported. GM’sd plant in Wentzville, Mo., could be spared becauser it’s the only plant wherre Chevrolet Express and GMC Savana vansare made, said Haig an auto industry analysgt with . “I would think that they woulfd keep thatproduct going,” he said. “Ihn the long run they are commercial vehicles and therer is usefor them.
They are used for construction fleets for majorutilitt companies, independent contactors and electricians and shuttld vehicles.” If GM were to move Wentzville’as operations to another plant, it wouldr have to redesign the vans to fit the platfor of other vehicles because the vans do not shar e parts with light trucks, for Stoddard said. Robert Wheeler, a spokesman for GM’s Wentzvillr plant, said he does not know which facilities willbe closed. we will likely hear this news at the same he said.
A representative from United Auto Worker Local whichrepresents 1,700 workers at the Wentzville plant, was not immediatelhy available to comment because union memberws were busy voting Thursday on UAW contractt concessions.